| Intravascular Infusion of Lidocaine: A Novel Way to Relieve Sudden Internal Carotid Artery Occlusion in Embolization of Intracranial Aneurysms. | |
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MedLine Citation:
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PMID: 22241594 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Sudden internal carotid artery (ICA) occlusive vasospasm is a serious complication of intracranial aneurysm embolization. Conventional spasmolysis with papaverine yields a generally poor outcome. We believe that arterial infusion of lidocaine may offer a better outcome. MATERIALS AND METHODS: We retrospectively reviewed the outcome of patients treated with either papaverine or lidocaine infusion for vasospasm during embolization. RESULTS: 14 patients undergoing intracranial aneurysm embolization had a ICA occlusive vasospasm. Among the 8 patients who received conventional treatment with papaverine the vasospasm improved partially in 5. In 3 cases, treatment was ineffective. 6 of the patients died within 3 days. 2 patients developed hemispheric infarction and underwent a decompressive craniectomy and subtotal resection of the infarct; 1 of these 2 patients died after 4 months and the other was severely disabled. In the 6 patients treated with lidocaine, spasmolysis and subsequent aneurysm treatment was succesful in 5. In 1 patient who had preoperative stenosis of the carotid artery proximal to the aneurysm spasmolysis failed. CONCLUSIONS: ICA occlusive spasm is an extremely serious and often lethal complication in embolization of intracranial aneurysms. Conventional treatment with papaverine has a poor outcome, whereas arterial infusion of lidocaine may achieve better results. |
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Authors:
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Qiao Yu Li; Wen Lin Xu; Yan Zhang; Pej Shan Lu; Zhi Cheng Yuan; Li Ping Zhan; Peng Wang; Xia Yu Lu; Bo Cheng |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: Central European neurosurgery Volume: - ISSN: 1868-4912 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101501500 Medline TA: Cen Eur Neurosurg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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The Affiliated People's Hospital of Jiangsu University, Department of Neurosurgery, Zhenjiang, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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