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Intravaginal naproxen in preterm labour: a preliminary study.
MedLine Citation:
PMID:  15512066     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In a preliminary study, the possibility that local inhibition of postaglandin formation may inhibit preterm labour was examined. An intravaginal cyclo-oxygenase inhibitor, naproxen sodium, 500 mg was used in cases of preterm labour. The gestational ages of the patients were between 27 and 34 weeks, and they included a triplet pregnancy unresponsive to beta-sympathomimetic therapy. Treatment with intravaginal naproxen sodium was associated with prolongation of pregnancy for more than 6 days in five out of seven patients. No untoward fetal or maternal side-effects were detected.
Authors:
G Elpek; M Uner; B Trak; Z Akinci; C G Zorlu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  18     ISSN:  0144-3615     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  1998 May 
Date Detail:
Created Date:  2004-10-29     Completed Date:  2005-04-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  236-7     Citation Subset:  -    
Affiliation:
Akdeniz University, School of Medicine, Department of Obsterics and Gynaecology, Antalya, Turkey.
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