Document Detail

Intravaginal and menstrual practices among women working in food and recreational facilities in Mwanza, Tanzania: implications for microbicide trials.
MedLine Citation:
PMID:  20665101     Owner:  NLM     Status:  MEDLINE    
Intravaginal and menstrual practices may potentially influence results of trials of microbicides for HIV prevention through effects on the vaginal environment and on adherence to microbicide and placebo products. As part of the feasibility study for the Microbicides Development Programme Phase 3 trial of a vaginal microbicide in Mwanza, a variety of quantitative and qualitative methods were used to describe these practices, associations with behaviour and underlying social norms among women working in food and recreational facilities. Intravaginal cleansing by inserting fingers and either water alone or soap and water was thought necessary to remove "uchafu" (dirt), referring to vaginal secretions, including menstrual blood and post-coital discharge. Vaginal cleansing was carried out within 2 hours after 45% of sex acts. Sexual enhancement practices were less common. Intravaginal and menstrual practices and associated behaviours and demographic factors should be measured and monitored throughout microbicide trials to enable analyses of their impacts on microbicide effectiveness.
Caroline F Allen; Nicola Desmond; Betty Chiduo; Lemmy Medard; Shelley S Lees; Andrew Vallely; Suzanna C Francis; David A Ross; Richard J Hayes
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AIDS and behavior     Volume:  14     ISSN:  1573-3254     ISO Abbreviation:  AIDS Behav     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-24     Completed Date:  2010-12-20     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  9712133     Medline TA:  AIDS Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1169-81     Citation Subset:  IM    
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MeSH Terms
Administration, Intravaginal
Anti-Infective Agents / therapeutic use*
Clinical Trials, Phase III as Topic
Focus Groups
HIV Infections / prevention & control*
Qualitative Research
Sexually Transmitted Diseases, Viral / prevention & control*
Vagina / drug effects*
Young Adult
Grant Support
G0701039//Medical Research Council; G0901756//Medical Research Council; MC_UP_A540_1108//Medical Research Council; //Medical Research Council
Reg. No./Substance:
0/Anti-Infective Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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