Document Detail


Intrauterine growth retardation: study of placental apoptosis.
MedLine Citation:
PMID:  15134306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the rate of apoptosis in the placental tissue of pregnancies complicated with intrauterine growth retardation (IUGR) and compared it with the results obtained in normal placentas. Our results clearly demonstrate a strongly increased rate of apoptosis in placentas of children born with IUGR, suggesting severe placental dysfunction. The significance of these findings needs further study.
Authors:
E Barrio; M T Calvo; A Romo; R Alvarez; J I Gutiérrez; J Naval; A Ferrández Longás
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  17 Suppl 3     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-05-11     Completed Date:  2005-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  451-6     Citation Subset:  IM    
Affiliation:
Department of Molecular Genetics, University Children's Hospital Miguel Servet, Zaragoza, Spain. barrioeva@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Apoptosis*
Female
Fetal Growth Retardation / pathology*
HL-60 Cells
Humans
In Situ Nick-End Labeling / methods
Pregnancy
Trophoblasts / pathology*,  ultrastructure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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