Document Detail

Intrauterine growth restriction.
MedLine Citation:
PMID:  16469319     Owner:  NLM     Status:  MEDLINE    
This study reviewed the screening, diagnosis, prophylaxis, and treatment of intrauterine growth restriction using the PubMed database for key words and the Cochrane database for systematic reviews. Identification of risk factors and measurement of symphysis-fundus height are currently the screening standards. Diagnosis is verified by ultrasonography. Accuracy of diagnosis may be improved by using customized fetal growth curves, symphysis-fundus height charts, and 3-dimensional ultrasonographic evaluation and measuring umbilical artery Doppler dimensional ultrasonographic evaluation measuring umbilical artery Doppler impedance. Prophylaxis with acetylsalicylic acid, started in the first or second trimester or combined with heparin before conception, may reduce the incidence of growth restriction in specific groups at high risk. Active management may reduce incidence in patients with mild to moderate asthma, and targeted treatment of infections may also be beneficial. Antenatal corticosteroid treatment also reduces the perinatal morbidity and mortality associated with IUGR. Bed rest has no demonstrated beneficial effects.
K Haram; E Søfteland; R Bukowski
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-02-08
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  93     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-06     Completed Date:  2006-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  5-12     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Amniotic Fluid
Aspirin / therapeutic use
Bed Rest
Fetal Development / physiology*
Fetal Growth Retardation / diagnosis*,  therapy*
Gestational Age
Heparin / therapeutic use
Hyperbaric Oxygenation
Imaging, Three-Dimensional
Prenatal Diagnosis*
Risk Factors
Ultrasonography, Prenatal / methods
Reg. No./Substance:
0/Adrenal Cortex Hormones; 50-78-2/Aspirin; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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