Document Detail


Intrauterine cerebral infarcts and bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor cleaning fluid during pregnancy.
MedLine Citation:
PMID:  14647172     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little is known about the effect of inhalation of methanol and other solvents on the pregnancy and the growth of the fetus. We report a preterm male infant who developed cerebral infarcts in utero, leading to large areas of bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor-cleaning fluid during pregnancy. The infant presented with acute fetal distress with significant metabolic acidosis at birth. Initial hypotonia was followed by generalized hypertonicity. This infant did not exhibit typical facial features of fetal alcohol syndrome.
Authors:
Des Bharti
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  23     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-03     Completed Date:  2004-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  693-6     Citation Subset:  IM    
Affiliation:
Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
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MeSH Terms
Descriptor/Qualifier:
Acetone / adverse effects
Acidosis / chemically induced
Cerebral Infarction / chemically induced*
Drug Combinations
Female
Fetal Diseases / chemically induced*
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / chemically induced*
Leukomalacia, Periventricular / chemically induced*,  ultrasonography
Male
Methanol / adverse effects
Pregnancy
Prenatal Exposure Delayed Effects*
Solvents / adverse effects*
Substance-Related Disorders / complications*
Toluene / adverse effects
Chemical
Reg. No./Substance:
0/Drug Combinations; 0/Solvents; 108-88-3/Toluene; 67-56-1/Methanol; 67-64-1/Acetone

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