| Intrauterine upper limb ischemia associated with fetal thrombophilia: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 20501986 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neonatal extremity gangrene is rare, even rarer are those born with evidence of intrauterine vascular occlusion. Intrauterine limb ischemia has been attributed to several etiological factors which include thromboembolic disease occluding the arteries of the affected limb or compression of the limb during intrauterine life. In this report, we present a case of brachioradial arterial thrombosis associated with mild homocysteinemia and double heterozygosity of methylenetetrahydrofolate reductase 677C-T and factor V Leiden gene mutations. We suggest investigating the neonates and their mothers for possible genetic prothrombotic risk factors when they present with intrauterine thrombosis as this issue is important for management and counseling. |
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Authors:
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Wadah M Khriesat; Hala S Al-Rimawi; Isam M Lataifeh; Suleimman Al-Sweedan; Eyad Baqain |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2010-05-21 |
Journal Detail:
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Title: Acta haematologica Volume: 124 ISSN: 1421-9662 ISO Abbreviation: Acta Haematol. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-07-28 Completed Date: 2010-08-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0141053 Medline TA: Acta Haematol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 1-4 Citation Subset: IM |
Copyright Information:
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Copyright 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Pediatrics, Jordan University of Science and Technology, Irbid, Jordan. wadahmd@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Fetal Diseases / etiology*, pathology Gangrene / congenital, etiology Humans Infant, Newborn Ischemia / etiology* Male Prenatal Diagnosis Thrombophilia / complications*, diagnosis, genetics Thrombosis / complications Upper Extremity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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