Document Detail

Intrathoracic petechiae in SIDS: a retrospective population-based 15-year study.
MedLine Citation:
PMID:  19291444     Owner:  NLM     Status:  MEDLINE    
Intrathoracic petechiae (IP), the most common gross finding in sudden infant death syndrome (SIDS) cases at autopsy, suggest upper airway obstruction (UAO) occurs during the terminal event. If true, IP would be expected more frequently among SIDS cases found face down compared to other face positions. We compare the rates of IP in SIDS cases found face down versus other face positions. A retrospective 15-year review of IP among all cases of SIDS occurring from 1991 through 2005 accessioned by the San Diego County Medical Examiner's Office was conducted. The presence or absence of IP was based on both gross and microscopic observations of the thoracic organs. The severity of thymic petechiae was scored semiquantitatively from microscopic observations. There were 489 SIDS cases during the study period. Sixteen of these were excluded because their deaths had been delayed by initially successful cardiopulmonary resuscitation. Among the remaining 473 SIDS cases, face position when found was specifically described for 332 (70%). Of 122 cases found face down, 112 (92%) had IP, compared to 85% (179) of 210 infants found with the face up or to the side (P = 0.06). The groups were not different with respect to age or gender, but the racial distribution was significantly different (P = 0.004). African-American infants comprised 28% of the found face down group compared to only 12% of the face up or side group. Our data do not support a role for external UAO caused by face positioning directly into the sleep surface in SIDS, but are consistent with internal UAO associated with apnea or gasping before dying of SIDS.
Henry F Krous; Elisabeth A Haas; Amy E Chadwick; Homeyra Masoumi; Christina Stanley
Related Documents :
2730124 - Hypoxic-ischaemic encephalopathy after near miss sudden infant death syndrome.
16328664 - Investigation of the sudden death of infants: a multicenter analysis.
10493424 - Water fluoridation and the sudden infant death syndrome.
2083104 - Factors involved in the pathogenesis of unexpected near miss events of infants (alte).
3183874 - Indirect test weighing: a new method for measuring overnight breast milk intakes in the...
2209834 - Intergenerational effects of the holocaust: patterns of engagement in the mother-daught...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-06
Journal Detail:
Title:  Forensic science, medicine, and pathology     Volume:  4     ISSN:  1547-769X     ISO Abbreviation:  -     Publication Date:  2008  
Date Detail:
Created Date:  2009-03-17     Completed Date:  2009-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101236111     Medline TA:  Forensic Sci Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  234-9     Citation Subset:  IM    
Rady Children's Hospital-San Diego, 3020 Children's Way, M5007, San Diego, CA 92123, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Airway Obstruction / etiology
Continental Population Groups / statistics & numerical data
Forensic Pathology
Infant, Newborn
Lung / pathology
Myocardium / pathology
Prone Position*
Purpura / pathology
Retrospective Studies
Sudden Infant Death / epidemiology,  pathology*
Thymus Gland / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Microscopical examination of particles on smoked cigarette filters.
Next Document:  Sudden unexpected death in a toddler with Williams syndrome.