Document Detail


Intratetrad mating and the evolution of linkage relationships.
MedLine Citation:
PMID:  15154546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mating among the immediate products of meiosis (intratetrad mating) is a common feature of many organisms with parthenogenesis or with mating-type determination in the haploid phase. Using a three-locus deterministic model we show that intratetrad mating, unlike other systems of mating, allows sheltering of deleterious recessive alleles even if there is only partial linkage between a mating locus and a load locus. Moreover, modifiers that reduce recombination between the load and mating-type locus will spread to fixation, even when there is no linkage disequilibrium between these loci in the population as a whole. This seeming contradiction to classical expectation is because partial linkage generates linkage disequilibrium among segregating loci within a tetrad, which then acts as the "mating unit."
Authors:
Janis Antonovics; Joseph Y Abrams
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Evolution; international journal of organic evolution     Volume:  58     ISSN:  0014-3820     ISO Abbreviation:  Evolution     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-05-24     Completed Date:  2004-06-28     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0373224     Medline TA:  Evolution     Country:  United States    
Other Details:
Languages:  eng     Pagination:  702-9     Citation Subset:  IM    
Affiliation:
Department of Biology, University of Virginia, Charlottesville, Virginia 22904, USA. antonovics@virginia.edu
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MeSH Terms
Descriptor/Qualifier:
Alleles*
Computer Simulation
Heterozygote
Meiosis / genetics*
Models, Genetic*
Mutation / genetics*
Reproduction / genetics
Selection, Genetic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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