| Intraspinal hemorrhage complicating oral anticoagulant therapy: an unusual case of cervical hematomyelia and a review of the literature. | |
| | |
MedLine Citation:
|
PMID: 10647763 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Intraspinal hemorrhage is a rare but dangerous complication of anticoagulant therapy. It must be suspected in any patient taking anticoagulant agents who complains of local or referred spinal pain associated with limb weakness, sensory deficits, or urinary retention. We describe a patient with hematomyelia, review the literature on hematomyelia and other intraspinal hemorrhage syndromes, and summarize intraspinal hemorrhage associated with oral anticoagulant therapy. The patient (a 62-year-old man) resembled previously described patients with hematomyelia in age and sex. However, he was unusual in having cervical rather than thoracic localization. As with intracranial bleeding, the incidence of intraspinal hemorrhage associated with anticoagulant therapy might be minimized by close monitoring and tight control of the intensity of anticoagulation. However, it is noteworthy that many of the reported cases were anticoagulated in the therapeutic range. If intraspinal hemorrhage is suspected, anticoagulation must be reversed immediately. Emergency laminectomy and decompression of the spinal cord appear mandatory if permanent neurologic sequelae are to be minimized. A high index of suspicion, prompt recognition, and immediate intervention are essential to prevent major morbidity and mortality from intraspinal hemorrhage. |
| | |
Authors:
|
V A Pullarkat; T Kalapura; M Pincus; R Baskharoun |
Related Documents
:
|
11714573 - Ossified thoracic spinal meningioma in childhood: a case report and review of the liter... 19073843 - Neurocutaneous melanosis: report of three cases and up-to-date review. 17187273 - Medulloblastoma in a child with duchenne muscular dystrophy. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Archives of internal medicine Volume: 160 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2000 Jan |
Date Detail:
|
Created Date: 2000-02-10 Completed Date: 2000-02-10 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 237-40 Citation Subset: AIM; IM |
Affiliation:
|
Department of Medicine, New York Methodist Hospital, Brooklyn, USA. vinodpullarkat@pol.net |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Administration, Oral Anticoagulants / administration & dosage, adverse effects* Diagnosis, Differential Hematoma, Epidural, Cranial / chemically induced, diagnosis, surgery Hematoma, Subdural / chemically induced, diagnosis, surgery Hemorrhage / chemically induced*, diagnosis, surgery Humans Laminectomy Magnetic Resonance Imaging Male Middle Aged Spinal Cord Vascular Diseases / chemically induced*, diagnosis, surgery Thromboembolism / drug therapy Warfarin / administration & dosage, adverse effects* |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants; 81-81-2/Warfarin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Low-molecular-weight heparin vs heparin in the treatment of patients with pulmonary embolism. Americ...
Next Document: Is functional upregulation of the 5-HT2B receptor in deoxycorticosterone acetate salt-treated rats b...