Document Detail

Intrasellar pituicytoma in a patient with other endocrine neoplasms.
MedLine Citation:
PMID:  11260629     Owner:  NLM     Status:  MEDLINE    
Considered a neoplasm of pituicytes, pituicytoma is a rare and distinct type of glioma that arises in the suprasellar space and within the sella turcica. Only 12 previously reported cases of pituicytoma are documented in the literature. We report an intrasellar pituicytoma in a 66-year-old man presenting with symptoms and radiologic appearance indistinguishable from a nonfunctional pituitary adenoma. The patient also had a medical history significant for parathyroid adenomas and follicular carcinoma of the thyroid. The intrasellar tumor had morphologic features of a pituicytoma, with interlacing fascicles and a storiform pattern much like a benign fibrous histiocytoma. Immunoreactivity for S100 was strong, but the tumor lacked intercellular collagen type IV. The differential diagnosis of a low-grade spindle cell lesion of the sellar space is discussed, and the literature is reviewed. A summary of the clinical and pathologic features of this case, as well as the 12 previously reported cases, is presented.
A B Schultz; D J Brat; N M Oyesiku; S B Hunter
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  125     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-22     Completed Date:  2001-04-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  527-30     Citation Subset:  AIM; IM    
Department of Pathology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA.
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MeSH Terms
Adenoma / diagnosis
Astrocytoma / chemistry,  pathology*
Diagnosis, Differential
Magnetic Resonance Imaging
Multiple Endocrine Neoplasia / pathology*
Pituitary Gland, Posterior / chemistry,  pathology*
Pituitary Neoplasms / chemistry,  pathology*
S100 Proteins / analysis
Sella Turcica / pathology*
Reg. No./Substance:
0/S100 Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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