Document Detail

Intraretinal gray lesions as a sign of reversible visual loss following prolonged ophthalmic artery hypoperfusion.
MedLine Citation:
PMID:  1838539     Owner:  NLM     Status:  MEDLINE    
A 49-year-old woman developed severe unilateral visual loss following carotid artery ligation for a carotid-cavernous fistula. The pathophysiology was presumed to be an ophthalmic artery steal caused by the fistula. This was confirmed when visual acuity was restored by a subsequent ligation of the ophthalmic artery, despite 2 weeks of profound visual loss and ocular ischemia. Superficial cotton-wool spots and deep gray intraretinal lesions developed in the retina during the period of ocular ischemia. We postulate that the deep intraretinal lesions are clinical manifestations of a zone of retinal microvascular watershed ischemia, and that their presence may be an important diagnostic guide to the presence of reversible ocular ischemia.
M Cherny; J O'Day; J Currie
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuro-ophthalmology     Volume:  11     ISSN:  0272-846X     ISO Abbreviation:  J Clin Neuroophthalmol     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-03-26     Completed Date:  1992-03-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8109051     Medline TA:  J Clin Neuroophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  228-32     Citation Subset:  IM    
Department of Neuro-ophthalmology, St. Vincent's Hospital, Fitzroy, Australia.
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MeSH Terms
Blindness / physiopathology*
Blood Circulation
Carotid Artery Diseases / physiopathology,  surgery
Craniocerebral Trauma / complications
Fluorescein Angiography
Fundus Oculi
Ischemia / pathology*,  physiopathology
Middle Aged
Ophthalmic Artery / physiopathology*
Postoperative Complications
Retinal Diseases / pathology*,  physiopathology
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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