| Intrapulmonary shunting in primary pulmonary hypertension: an observation in two patients treated with epoprostenol sodium. | |
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MedLine Citation:
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PMID: 9674493 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms and survival. This report describes two patients with primary pulmonary hypertension treated with epoprostenol in whom intrapulmonary shunting and severe hypoxemia occurred. Intrapulmonary shunting was confirmed by contrast echocardiography showing delayed appearance of bubbles in the left cardiac chambers after peripheral venous injection of agitated saline solution. |
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Authors:
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P F Castro; R C Bourge; D C McGiffin; R L Benza; P Fan; N B Pinkard; M D McGoon |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 114 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1998 Jul |
Date Detail:
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Created Date: 1998-08-05 Completed Date: 1998-08-05 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 334-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, The University of Alabama at Birmingham, 35294, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anoxia
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etiology Antihypertensive Agents / administration & dosage, therapeutic use* Contrast Media / administration & dosage Echocardiography Epoprostenol / administration & dosage, therapeutic use* Hemangioma, Capillary / pathology Humans Hypertension, Pulmonary / drug therapy, physiopathology* Infusions, Intravenous Injections, Intravenous Lung Neoplasms / pathology Lung Transplantation Male Middle Aged Pulmonary Circulation / drug effects, physiology* Pulmonary Fibrosis / pathology Sodium Chloride / administration & dosage, diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 0/Contrast Media; 35121-78-9/Epoprostenol; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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