Document Detail

Intraplacental choriocarcinoma in a term placenta with both maternal and infantile metastases: a case report and review of the literature.
MedLine Citation:
PMID:  17005243     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Intraplacental choriocarcinoma is rare, and usually results in maternal metastasis at the time of diagnosis. Intraplacental choriocarcinoma involves both mother and infant is extremely rare. There was only one case report of intraplacental choriocarcinoma with confirmed metastases involving both the mother and the infant. CASE: We describe a second case of intraplacental choriocarcinoma in a term placenta with both maternal and infantile metastases. Grossly, the primary lesion of the placenta resembled an old infarct. Microscopically, clusters of malignant trophoblasts arose from residual normal chorionic villi and infiltrated into the intervillous spaces. Both the mother and the infant received chemotherapy and were alive without disease after one year's follow-up. CONCLUSION: The optimal treatment for intraplacental choriocarcinoma is controversial. However, aggressive chemotherapy is suggested for patients with metastatic disease.
Jianping Liu; Lina Guo
Related Documents :
7595313 - Applications of minisatellite variant repeat (mvr) mapping for maternal identification ...
16055853 - Steroids in allantoic waste: an integrated measure of steroid exposure in ovo.
1941403 - Selenium absorption and retention by very-low-birth-weight infants: studies with the ex...
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2006-09-26
Journal Detail:
Title:  Gynecologic oncology     Volume:  103     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1147-51     Citation Subset:  IM    
Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, P.R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Choriocarcinoma / diagnosis*,  drug therapy,  secondary
Diagnosis, Differential
Infant, Newborn
Lung Neoplasms / diagnosis*,  drug therapy,  secondary
Neoplasm Metastasis
Peritoneal Neoplasms / diagnosis*,  drug therapy,  secondary
Placenta Diseases / diagnosis*,  drug therapy,  pathology
Pregnancy Complications, Neoplastic / diagnosis*,  drug therapy,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hyperhomocysteinemia is a risk factor of recurrent coronary event in young patients irrespective to ...
Next Document:  Ovarian cancer: patterns of surgical care across the United States.