| Intraperitoneal Fat Is Associated With Thickening of the Thoracic Aorta in Individuals at High Risk for Cardiovascular Events. | |
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MedLine Citation:
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PMID: 21720433 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Increased intraperitoneal (IP) fat is associated with increased cardiovascular (CV) risk, but mechanisms for this increase in risk are not completely established. We performed this study to assess whether IP fat is associated with ascending aortic wall thickness (AOWT), a risk factor for CV events. Four hundred and forty-one consecutive participants, aged 55-85 years, with risk factors for CV events underwent magnetic resonance measures of AOWT and abdominal fat (subcutaneous (SC) fat + IP fat). For the ascending aorta, mean wall thickness of the 4th quartile of the IP fat was higher relative to the 1st quartile (P ≤ 0.001). This difference persisted after accounting for SC fat (P ≤ 0.001), as well as age, gender, height, weight, smoking, diabetes, hypertension, low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and C-reactive protein (CRP) (P < 0.03). Elevated IP fat volume is associated with an increase in ascending AOWT, a condition that promotes CV events in middle aged and elderly adults. |
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Authors:
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Haroon L Chughtai; Timothy M Morgan; Craig A Hamilton; Charaslak Charoenpanichkit; Jingzhong Ding; Tina E Brinkley; W Gregory Hundley |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-30 |
Journal Detail:
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Title: Obesity (Silver Spring, Md.) Volume: - ISSN: 1930-7381 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-7-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101264860 Medline TA: Obesity (Silver Spring) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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