Document Detail


Intrapatient Comparison of 308-nm Monochromatic Excimer Light and Localized Narrow-Band UVB Phototherapy in the Treatment of Vitiligo: A Randomized Controlled Trial.
MedLine Citation:
PMID:  22269666     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Limited data are available about the use of 308-nm monochromatic excimer light (MEL) and localized 311-nm narrow-band ultraviolet B (NB-UVB) in the treatment of vitiligo. The aim of this study was to evaluate the efficacy of 308-nm MEL versus localized 311-nm NB-UVB in vitiligo patients. Methods: Eleven patients participated in this prospective intrapatient placebo-controlled randomized trial. In each patient, 3 lesions were selected and treated with NB-UVB, MEL and placebo during 24 sessions, respectively. Repigmentation was evaluated clinically and by objective surface measurement. Results: Twenty percent of the lesions treated with NB-UVB achieved repigmentation scores above 50%. None of the lesions treated with MEL achieved a repigmentation higher than 50% after 24 sessions. Conclusion: Localized 311-nm NB-UVB is effective in the treatment of vitiligo. It should be considered for localized vitiligo as it is easily accessible. In this study the efficacy of localized 311-nm NB-UVB was superior to 308-nm MEL.
Authors:
E Verhaeghe; E Lodewick; N van Geel; J Lambert
Related Documents :
21902296 - Ustekinumab: a review of its use in the management of moderate to severe plaque psoriasis.
22054636 - Psychosocial risk factors for hospital readmission in copd patients on early discharge ...
2023746 - Aminocaproic acid versus prednisone for the treatment of traumatic hyphema. a randomize...
21742556 - Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sc...
2467496 - Acrivastine versus hydroxyzine in the treatment of cholinergic urticaria. a placebo-con...
24528276 - Early intervention after perinatal stroke: opportunities and challenges.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-24
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  -     ISSN:  1421-9832     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Affiliation:
Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Novel nanocomposite stent coating releasing resveratrol and quercetin reduces neointimal hyperplasia...
Next Document:  Chromosomal 16p microdeletion in Rubinstein-Taybi syndrome detected by oligonucleotide-based array c...