Document Detail

Intrapartum infusion of aqueous glucose solution, transplacental hyponatraemia and risk of neonatal jaundice.
MedLine Citation:
PMID:  6487563     Owner:  NLM     Status:  MEDLINE    
Cord serum sodium levels in three groups of 278 singleton infants, born vaginally at term, were correlated with the incidence of jaundice (serum bilirubin greater than or equal to 85 mumol/1) in the first 3 days of life. Of the 278 infants, 87 were born to mothers who were given infusions of 5% or 10% glucose in water during labour (group I), 90 were born to mothers who received glucose solution as a vehicle for oxytocin (group II), and 101 to mothers who did not receive any intravenous fluid therapy (control group). Jaundice was seen significantly more frequently in groups I (28/87, 32%) and II infants (30/90, 33%) than in the control group (12/101, 12%) (P less than 0.01), but when analysed in relation to cord serum sodium levels, the prevalence of jaundice in the normonatraemic infants (serum sodium greater than or equal to 131 mmol/1) was similar in the three groups. On the other hand, in groups I and II jaundice occurred about 3.5 times more frequently in the hyponatraemic infants [group I (17/32, 53%) and II (20/39, 51%)] than in the normonatraemic infants (P less than 0.01). The difference was not associated with any other perinatal or neonatal characteristic.
S Singhi; E Chookang; J S Hall
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  91     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-28     Completed Date:  1984-11-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1014-8     Citation Subset:  AIM; IM    
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MeSH Terms
Fetal Blood / analysis
Fluid Therapy / adverse effects*
Glucose / adverse effects*
Hyponatremia / complications*,  etiology
Infant, Newborn
Jaundice, Neonatal / etiology*
Oxytocin / administration & dosage
Prospective Studies
Sodium / blood
Reg. No./Substance:
0/Vehicles; 50-56-6/Oxytocin; 50-99-7/Glucose; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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