Document Detail


Intraparotid neurofibroma: review of the literature.
MedLine Citation:
PMID:  21453645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To perform a literature review of intra-parotid neurofibromas. These tumours present a challenge because of their risk of malignant transformation and their high probability of operative facial nerve compromise.
DESIGN: A description of one case of intraparotid neurofibroma. A systematic MEDLINE review was performed to document all reported cases.
SETTING: Pediatric tertiary care centre.
METHODS: An 14-month-old boy was referred with a nontender right-sided 4 × 2.5 cm preauricular mass, which was slowly increasing in size for 8 months. No facial nerve compromise was present.
MAIN OUTCOME MEASURES: During superficial parotidectomy, the mass was found to involve the facial nerve and complete resection was performed, on which a cerebrospinal fluid (CSF) leak originating from the stylomastoid foramen occurred. Mastoidectomy revealed an intramastoid division of the facial nerve. The leak coming from the facial nerve was successfully controlled with anastomosis of the major division with the distal nerves.
RESULTS: Histopathologic analysis revealed a diffuse neurofibroma. Twenty-two previous cases of intraparotid neurofibroma have been described, although this is the first reported case of the diffuse subtype. Preoperative fine-needle aspiration was inconclusive, and incisional biopsy was dangerous.
CONCLUSION: It seems prudent to delay surgery for asymptomatic pediatric patients with facial neurofibroma. Surgery with primary facial nerve grafting is an effective option for patients with facial function of grade III or worse or when the tumour is large, disfiguring, and aggressive. Potential complications of treatment vary depending on the location of the tumour. These include disease recurrence, facial nerve compromise, and CSF leak.
Authors:
Owen Woods; Chantal Giguère; Issam Saliba
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale     Volume:  40     ISSN:  1916-0216     ISO Abbreviation:  J Otolaryngol Head Neck Surg     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-01     Completed Date:  2011-08-09     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  101479544     Medline TA:  J Otolaryngol Head Neck Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  104-12     Citation Subset:  IM    
Affiliation:
Otorhinolaryngology Service, Sainte-Justine University Hospital Centre, Montreal University, Montreal, QC.
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MeSH Terms
Descriptor/Qualifier:
Cranial Nerve Neoplasms / pathology*
Facial Nerve Diseases / pathology*
Humans
Infant
Male
Neurofibroma / pathology*
Parotid Gland / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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