Document Detail

Intraorbital corticosteroid injection for orbital reactive lymphoid hyperplasia.
MedLine Citation:
PMID:  23348726     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of this study is to assess the utility of intraorbital injection of triamcinolone acetonide as a primary treatment option for orbital reactive lymphoid hyperplasia (RLH).
PATIENTS AND METHOD: Retrospective, single-centre, interventional case series.
RESULTS: Intraorbital injection of triamcinolone acetonide was associated with complete resolution of all symptoms and signs in four cases (80%). This was achieved with a single injection in two cases and with two injections in another two cases. Radiological resolution was confirmed in one case. One case developed bilateral multifocal orbital RLH lesions 1 month after the second injection.
CONCLUSION: Intraorbital injection of corticosteroid may be a useful treatment option for orbital RLH, and may have a role as a first-line therapy in RLH of the anterior orbit. A significant proportion of patients may require repeat injections to achieve resolution. A larger prospective study is required to validate our findings.
N H Andrew; D Kearney; D Selva
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2013-01-25
Journal Detail:
Title:  Eye (London, England)     Volume:  27     ISSN:  1476-5454     ISO Abbreviation:  Eye (Lond)     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-11     Completed Date:  2013-09-10     Revised Date:  2014-04-01    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  561-3     Citation Subset:  IM    
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MeSH Terms
Adrenal Cortex Hormones / administration & dosage*
Injections, Intraocular
Middle Aged
Orbital Diseases / drug therapy*
Pseudolymphoma / drug therapy*
Retrospective Studies
Treatment Outcome
Triamcinolone Acetonide / administration & dosage*
Reg. No./Substance:
0/Adrenal Cortex Hormones; F446C597KA/Triamcinolone Acetonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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