| Intraoperative monitoring of IMA flow: what does it mean? | |
| | |
MedLine Citation:
|
PMID: 9203589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: This study examines whether the measurement of internal thoracic artery (ITA) graft flow can determine the adequacy of the ITA-left anterior descending coronary artery (LAD) anastomosis. METHODS: To study a wide range of clinical problems, we used a computer simulation of the cardiovascular system. The model included a time-varying elastance model of the heart, a systemic circulation represented by a multielement nonlinear model of the aorta and its major branches, a nonlinear model of the LAD circulation, and a model of the ITA bypass graft. RESULTS: With a mild LAD stenosis, ITA graft flow was low and flow reversal occurred. As the percent stenosis increased, ITA flow and the percentage of ITA-to-total LAD flow increased. The ITA graft helped to maintain resting LAD blood flow. A partial obstruction (40%) at the ITA-LAD anastomosis reduced ITA graft flow at similar levels of LAD stenosis. However, overlap in flow values comparing a normal with a partially obstructed anastomosis occurred. CONCLUSIONS: Flow patterns in the ITA are highly dependent on the degree of stenosis of the LAD as well as the integrity of the anastomosis. The predictive power of ITA flow measurement increases with severe stenosis or total occlusion of the proximal LAD and with high coronary blood flow demands. |
| | |
Authors:
|
O Barnea; W P Santamore |
Related Documents
:
|
17682729 - Particle image velocimetry measurement in the model of vascular anastomosis. 8773969 - Screening for dialysis access graft malfunction: comparison of physical examination wit... 3440729 - Thermodynamic correlates of hot tip laser angioplasty. 9788139 - Visualization of flow patterns from stents and stent-grafts in an in vitro flow-model. 10706829 - Effects of hypertonic saline-dextran solution on regional blood flow and thrombogenicit... 14621809 - Activation of the alternative pathway of complement is an important component of hypera... 6227429 - A pulsed doppler echocardiographic method for calculating pulmonary and systemic blood ... 22502579 - Validation of diffuse correlation spectroscopic measurement of cerebral blood flow usin... 3704389 - The role of 2,3-dpg in the oxygen transport at altitude. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Annals of thoracic surgery Volume: 63 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1997 Jun |
Date Detail:
|
Created Date: 1997-07-17 Completed Date: 1997-07-17 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: S12-7 Citation Subset: AIM; IM |
Affiliation:
|
Biomedical Engineering Department, Tel Aviv University, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anastomosis, Surgical Blood Flow Velocity* Computer Simulation Coronary Artery Bypass* Coronary Circulation Coronary Disease / physiopathology, surgery Humans Models, Cardiovascular Monitoring, Intraoperative* Thoracic Arteries / physiology*, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical assessment of functional stenosis severity: use of coronary pressure measurements for the d...
Next Document: Role of myocardial protection for coronary artery bypass grafting on the beating heart.