Document Detail


Intraoperative measurement of pericardial constraint: role in ventricular diastolic mechanics.
MedLine Citation:
PMID:  3782635     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pressure of pericardial constraint was measured in 20 patients undergoing elective cardiac surgery (10 in Group I with normal cardiac size; 10 in Group II with cardiomegaly) using a catheter with a collapsible latex end balloon. Right atrial pressure and other hemodynamic variables including right ventricular stroke work index were also measured before and after the pericardium was widely opened. The pericardium was grossly normal in all patients and only small physiologic effusions were present. In Group I mean pericardial pressure was 8 +/- 2 mm Hg as was mean right atrial pressure. In Group II mean pericardial pressure was 6 +/- 2 mm Hg versus mean right atrial pressure of 10 +/- 5 mm Hg (p less than 0.05). Excluding 2 of the 20 patients with outlying data, pericardial pressure showed linear correlation with right atrial pressure (r = 0.689). In Group I right ventricular stroke work index rose from 5.0 +/- 2.0 to 6.4 +/- 2.1 g-m/m2 (p less than 0.01) after pericardiotomy with no significant increase in mean right atrial pressure; similar findings in Group II were consistent with removal of external constraint. Thus, even in the absence of an abnormal effusion the normal pericardium exerts a significant pressure on the heart, which is often similar in magnitude to right atrial pressure. In certain notable exceptions, however, right atrial pressure far exceeds pericardial pressure. Such pericardial constraint has important implications for ventricular diastolic mechanics.
Authors:
C M Boltwood; A Skulsky; D C Drinkwater; S Lang; D G Mulder; P M Shah
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  8     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1987-01-05     Completed Date:  1987-01-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1289-97     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Biomechanics
Cardiac Surgical Procedures*
Diastole*
Heart Ventricles
Hemodynamics
Humans
Intraoperative Period
Myocardial Contraction*
Pericardium / physiopathology*,  surgery
Regression Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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