| Intraoperative management of pulmonary hypertension and associated right heart failure. | |
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MedLine Citation:
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PMID: 19907315 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE OF REVIEW: Pulmonary hypertension is associated with high perioperative morbidity and mortality. Management of intraoperative pulmonary hypertension, along with frequently associated right heart failure, is extremely challenging. We now review the pathophysiology and clinical management of pulmonary hypertension, and associated right heart failure. RECENT FINDINGS: Pulmonary hypertension results from a combination of both environmental and genetic influences. Current treatments include the use of pulmonary vasodilators, optimization of inotropic agents to support cardiac function, maintenance of perfusion to the right ventricle, and correction of any physiologically detrimental conditions (e.g. hypoxemia, hypercarbia, acidosis, hypothermia, hypervolemia, and increased intrathoracic pressure). SUMMARY: Knowledge of pulmonary hypertension pathophysiology and treatment modalities will not only improve intraoperative management but also reduce postoperative morbidity and mortality. |
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Authors:
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Claire Gordon; Charles D Collard; Wei Pan |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in anaesthesiology Volume: 23 ISSN: 1473-6500 ISO Abbreviation: Curr Opin Anaesthesiol Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2009-12-25 Completed Date: 2010-03-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8813436 Medline TA: Curr Opin Anaesthesiol Country: United States |
Other Details:
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Languages: eng Pagination: 49-56 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Baylor College of Medicine, Houston, Texas, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiotonic Agents
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therapeutic use* Heart Failure / drug therapy*, etiology, physiopathology Humans Hypertension, Pulmonary / complications, drug therapy*, physiopathology Intraoperative Complications / drug therapy*, physiopathology Vasodilator Agents / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Cardiotonic Agents; 0/Vasodilator Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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