| Intraoperative graft flow measurements during coronary artery bypass surgery predict in-hospital outcomes. | |
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MedLine Citation:
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PMID: 18467427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transit-time flowmetry enables immediate intraoperative assessment of blood flow parameters in coronary artery bypass grafts (CABG). The present study assesses the predictive value of measured graft flows on early and medium-term outcomes. All cardiac surgery patients with measured graft flows were included. The last intraoperative flow measurements recorded using the Medtronic Butterfly Flowmetry system were used for analysis. Patients were separated into two groups: patients with normal flow in all grafts or patients with abnormal flow > or =1 graft. Any pulsatility index (pulsatility index=min-max flow/mean flow) < or =5 was determined to be normal flow. The study population included 985 patients. Nineteen percent of patients had abnormal flow in > or =1 graft. Overall in-hospital mortality was 4.7% and not significant between the two groups. After adjusting for covariates, the in-hospital composite outcome for adverse cardiac events was more prevalent in the abnormal flow group (31% vs. 17%; P<0.0001) with an odds ratio of 1.7 (CI 1.1-2.7). Survivors to discharge had a mean follow-up of 1.8 years. However, abnormal flow was not an independent predictor of the medium-term mortality and readmission to hospital for cardiac reason following discharge. Our findings suggest that abnormal flows measured intraoperatively are independently associated with short-term in-hospital adverse outcome. |
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Authors:
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Christine Herman; John A Sullivan; Karen Buth; Jean-Francois Legare |
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Publication Detail:
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Type: Journal Article Date: 2008-05-08 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 7 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-07-30 Completed Date: 2008-10-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 582-5 Citation Subset: IM |
Affiliation:
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Department of Surgery, Division of Cardiac Surgery, Dalhousie University, Halifax, NS, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Flow Velocity Cardiovascular Diseases / diagnosis*, etiology, mortality, physiopathology Coronary Artery Bypass / adverse effects*, mortality Coronary Circulation* Female Hospital Mortality Humans Intraoperative Care Male Middle Aged Odds Ratio Predictive Value of Tests Proportional Hazards Models Pulsatile Flow Reoperation Rheology / methods* Risk Assessment Time Factors Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Interact Cardiovasc Thorac Surg. 2008 Aug;7(4):585
[PMID:
18664663
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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