| Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion. | |
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MedLine Citation:
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PMID: 20381368 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Local recurrent of disease in advanced carcinomas of the head and neck is strongly correlated with the presence of positive or close resection margins after operative treatment. The purpose of this study is to present a new method of assessing resection margins intraoperatively using image-guided surgery based on positron emission tomography/computed tomography (PET/CT) image fusion. In 6 patients who underwent surgical treatment of head and neck stage for T4a-T4b carcinomas PET/CT image fusion was done on the workstation of a 3D-navigation system. Intraoperative image-guided navigation of the defect following surgical ablation of the tumour was performed in every patient. Intraoperative navigation of the ablative defect showed an unsafe resection margin in 4 patients. In three of these patients additional image-guided resection allowed local control of the tumour to be achieved. In one patient additional resection was not possible due to skull base invasion. The histopathological exam of the four tumour specimens confirmed positive or close resection margins. The current results suggest that intraoperative control of the surgical margins using a 3D-navigation system based on PET/CT image fusion can be a useful tool to assess and improve local control in advanced cancer of the head and neck. |
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Authors:
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Matthias Feichtinger; Mauro Pau; Wolfgang Zemann; Reingard Maria Aigner; Hans Kärcher |
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Publication Detail:
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Type: Journal Article Date: 2010-04-08 |
Journal Detail:
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Title: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery Volume: 38 ISSN: 1878-4119 ISO Abbreviation: J Craniomaxillofac Surg Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8704309 Medline TA: J Craniomaxillofac Surg Country: Scotland |
Other Details:
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Languages: eng Pagination: 589-94 Citation Subset: D; IM |
Copyright Information:
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Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Oral and Maxillofacial Surgery, Medical University of Graz, Austria. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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