| Intraoperative contrast echocardiography with intravenous optison does not cause hemodynamic changes during cardiac surgery. | |
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MedLine Citation:
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PMID: 11391288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The echocardiographic contrast agent Optison may be useful in patients undergoing cardiac surgery. This study investigates its effects on hemodynamics, cardiac performance, and oxygenation in this group of patients. METHODS: Parameters of hemodynamic stability, cardiac performance, and oxygenation were measured in 57 patients by transesophageal echocardiography, electrocardiography, invasive arterial blood pressure and central venous pressure monitoring, capnography, pulsoximetry, and pulmonary artery catheter before and 5 and 10 minutes after an intravenous bolus of 0.3 mL of Optison. RESULTS: No statistically significant differences in ST-segment changes, heart rate, arterial and central venous pressure, peripheral oxygen saturation, cardiac index, left ventricular ejection fraction, and regional wall motion were seen 5 and 10 minutes after injection of Optison compared with baseline parameters. CONCLUSIONS: Optison did not cause clinically important changes in parameters of hemodynamic stability, cardiac performance, and oxygenation in our patients. The intraoperative use of intravenous Optison appears to be safe in patients undergoing cardiac surgery, including in the use of cardiopulmonary bypass. |
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Authors:
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J M Erb; J S Shanewise |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 14 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-06-06 Completed Date: 2001-07-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 595-600 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, German Heart Institute, Berlin. erbk@dhzb.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Albumins / pharmacology* Blood Pressure / drug effects Cardiac Surgical Procedures* Cardiopulmonary Bypass Contrast Media / pharmacology* Fluorocarbons / pharmacology* Heart / drug effects* Heart Rate / drug effects Hemodynamics / drug effects Humans Intraoperative Period Middle Aged Stroke Volume / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Albumins; 0/Contrast Media; 0/FS 069; 0/Fluorocarbons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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