| Intraoperative changes of mucosal pCO2 during gastric tube formation. | |
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MedLine Citation:
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PMID: 11685561 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The formation of a gastric tube after esophagectomy with ligation of the left gastric artery and resection of the lesser curvature is associated with microcirculatory changes, especially in the anastomotic region of the fundus. This influences the healing of the esophagogastrostomy. The presented prospective protocol was designed to assess continuous tonometry as a tool to demonstrate microcirculatory changes during gastric tube formation. In 15 patients with esophageal carcinoma, pCO2 of the gastric mucosa (pCO2i) was measured intraoperatively during formation of a gastric tube. This was done by a nasogastric tube with a silicon balloon connected to a Tonocap recirculating gas analyser. pCO2i measurements were compared for a period of 90 min before and after ligation of the left gastric artery and correlated to the corresponding end expiratory pCO2 (pCO2e). In 14 of 15 patients examined (93.3%), an increase of pCO2i after ligation of the left gastric artery was demonstrated. pCO2i (mean+/-SD) before ligation of the left gastric artery (87 measurements: 40.6+/-7.5 mmHg; range, 29-67 mmHg) was significantly lower (P<0.001) compared to the mean pCO2i after ligation of the left gastric artery (88 measurements: 49.1+/-10.2 mmHg; range, 31-79 mmHg). Continuous tonometry is a valid method to detect changes in mucosal pCO2 during gastric tube formation and should be assessed to monitor the gastric interposition graft during the postoperative course. |
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Authors:
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W Schröder; D Stippel; K T Beckurts; M Lacher; C Gutschow; A H Hölscher |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie Volume: 386 ISSN: 1435-2443 ISO Abbreviation: Langenbecks Arch Surg Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-10-30 Completed Date: 2001-12-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9808285 Medline TA: Langenbecks Arch Surg Country: Germany |
Other Details:
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Languages: eng Pagination: 324-7 Citation Subset: IM |
Affiliation:
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Department of Visceral and Vascular Surgery, University of Cologne, Joseph-Stelzmann-Str. 9, 50931 Cologne, Germany. Wolfgang.Schroeder@Uni-Koeln.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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surgery Adult Aged Anastomosis, Surgical / adverse effects Carbon Dioxide / blood* Carcinoma, Squamous Cell / surgery Celiac Artery / anatomy & histology, surgery Clinical Protocols Esophageal Neoplasms / surgery Esophagostomy / adverse effects, methods* Female Gastric Mucosa / blood supply* Gastrostomy / adverse effects, methods* Humans Ligation / adverse effects Male Manometry / methods* Microcirculation Middle Aged Monitoring, Intraoperative / methods* Wound Healing |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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