Document Detail

Intraoperative blood salvage in excisional burn surgery: an analysis of yield, bacteriology, and inflammatory mediators.
MedLine Citation:
PMID:  9710727     Owner:  NLM     Status:  MEDLINE    
The diminution of intraoperative hemorrhage remains a fundamental goal of the burn surgeon. We hypothesized that intraoperative blood salvage during burn excisions would be feasible if predicated on yield, bacteriology, and concentration of inflammatory mediators in the washed product. Reinfusion of culture-positive blood has a clear precedent in the trauma literature. Eight operations with immediate and complete collection of shed blood into a cell-saver device were prospectively studied. A median salvage rate of 43% of total shed red blood cells was estimated to have been recovered. Actual volumetric measurement of intraoperative blood loss was achieved. Bacterial contamination was consonant with the abdominal trauma experience. The levels of C3a, C5a, TNF alpha, and IL-1 beta in the final cell-saver product were all found to be at clinically insignificant levels.
J C Jeng; T M Boyd; K A Jablonski; J D Harviel; M H Jordan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of burn care & rehabilitation     Volume:  19     ISSN:  0273-8481     ISO Abbreviation:  J Burn Care Rehabil     Publication Date:    1998 Jul-Aug
Date Detail:
Created Date:  1998-10-19     Completed Date:  1998-10-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8110188     Medline TA:  J Burn Care Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  305-11     Citation Subset:  IM    
Burn Center, Washington Hospital Center, Washington DC 20010, USA.
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MeSH Terms
Blood / microbiology*
Blood Loss, Surgical / prevention & control*
Blood Transfusion, Autologous
Burns / surgery*
Complement C3a / analysis
Complement C5a / analysis
Inflammation Mediators / blood*
Interleukin-1 / blood
Intraoperative Period
Middle Aged
Prospective Studies
Tumor Necrosis Factor-alpha / analysis
Reg. No./Substance:
0/Inflammation Mediators; 0/Interleukin-1; 0/Tumor Necrosis Factor-alpha; 80295-42-7/Complement C3a; 80295-54-1/Complement C5a

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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