Document Detail


Intraoperative blood salvage in excisional burn surgery: an analysis of yield, bacteriology, and inflammatory mediators.
MedLine Citation:
PMID:  9710727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The diminution of intraoperative hemorrhage remains a fundamental goal of the burn surgeon. We hypothesized that intraoperative blood salvage during burn excisions would be feasible if predicated on yield, bacteriology, and concentration of inflammatory mediators in the washed product. Reinfusion of culture-positive blood has a clear precedent in the trauma literature. Eight operations with immediate and complete collection of shed blood into a cell-saver device were prospectively studied. A median salvage rate of 43% of total shed red blood cells was estimated to have been recovered. Actual volumetric measurement of intraoperative blood loss was achieved. Bacterial contamination was consonant with the abdominal trauma experience. The levels of C3a, C5a, TNF alpha, and IL-1 beta in the final cell-saver product were all found to be at clinically insignificant levels.
Authors:
J C Jeng; T M Boyd; K A Jablonski; J D Harviel; M H Jordan
Related Documents :
16865027 - Autologous blood injection and botulinum toxin for resistant plantar fasciitis accompan...
15833517 - Intraoperative cell salvage during radical prostatectomy is not associated with greater...
3162577 - Preoperative donation of autologous blood: technique, experience, and community applica...
12675727 - Activation of the complement system by different autologous transfusion devices: an in ...
11754137 - A comparative study of bovine blood and milk neutrophil functions with luminol-dependen...
7847607 - Studies of the oxidation of ethanol to acetaldehyde by oxyhemoglobin using fluorigenic ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of burn care & rehabilitation     Volume:  19     ISSN:  0273-8481     ISO Abbreviation:  J Burn Care Rehabil     Publication Date:    1998 Jul-Aug
Date Detail:
Created Date:  1998-10-19     Completed Date:  1998-10-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8110188     Medline TA:  J Burn Care Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  305-11     Citation Subset:  IM    
Affiliation:
Burn Center, Washington Hospital Center, Washington DC 20010, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Blood / microbiology*
Blood Loss, Surgical / prevention & control*
Blood Transfusion, Autologous
Burns / surgery*
Complement C3a / analysis
Complement C5a / analysis
Humans
Inflammation Mediators / blood*
Interleukin-1 / blood
Intraoperative Period
Middle Aged
Prospective Studies
Tumor Necrosis Factor-alpha / analysis
Chemical
Reg. No./Substance:
0/Inflammation Mediators; 0/Interleukin-1; 0/Tumor Necrosis Factor-alpha; 80295-42-7/Complement C3a; 80295-54-1/Complement C5a

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Lymph isolated from a regional scald injury produces a negative inotropic effect in dogs.
Next Document:  Rates of dysfunction in parents of pediatric patients with burns.