| Intraoperative blood and fluid administration differences in primary liver transplantation versus liver retransplantation. | |
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MedLine Citation:
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PMID: 21729810 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVES: Liver retransplantation (Re-LT) is the effective therapy for irreversible liver graft failure after primary liver transplantation (LT). The challenges faced by the operative team in the Re-LT setting have been seldom elucidated. Our aim is to analyze the differences in fluid management in primary LT and Re-LT during the surgical procedure. METHODS: The anesthesia charts of 16 patients who underwent both primary LT and Re-LT at our center in the space from October 1995 to May 2009 were analyzed. Group 1 (GI) consisted of patients who underwent primary LT, whereas patients in Group 2 (GII) were patients in GI but underwent Re-LT. GI was further divided into two subgroups depending on whether they had previous abdominal surgery before primary LT (GIB) or not (GIA). Wilcoxon signed-ranks test was used to compare GI and GII, and GIA and GIB. A p value less than 0.05 was regarded as significant. Data were given as mean±standard deviation. RESULTS: Blood loss was significantly increased from 48.9±106mL/kg in GI to 251.5±242mL/kg in GII. Consequently more blood products, crystalloids, sodium bicarbonate, calcium chloride, and neosynephrine were required to support the hemodynamics in GII. In GI, GIB tended to bleed more and required more blood transfusions than GIA. CONCLUSION: More bleeding is expected in Re-LT than primary LT. Additional anesthetic personnel, more intravenous lines, and blood and blood products should be readily available to deal with the emergent fluid and hemodynamic resuscitations in anesthesia for Re-LT. |
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Authors:
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Sheng-Chun Yang; Chao-Long Chen; Chih-Hsien Wang; Chia-Jung Huang; Kwok-Wai Cheng; Shao-Chun Wu; Bruno Jawan |
Publication Detail:
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Type: Journal Article Date: 2011-06-24 |
Journal Detail:
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Title: Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists Volume: 49 ISSN: 1875-452X ISO Abbreviation: Acta Anaesthesiol Taiwan Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-07-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101214918 Medline TA: Acta Anaesthesiol Taiwan Country: China (Republic : 1949- ) |
Other Details:
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Languages: eng Pagination: 50-3 Citation Subset: IM |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
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Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, R.O.C. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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