| Intraoperative autologous transfusion of hemolyzed blood. | |
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MedLine Citation:
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PMID: 19535693 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During two cases of lumbar spine surgery with instrumentation, we used intraoperative autologous transfusion (IAT), resulting in hemolysis during collection and hemoglobinuria and coagulation abnormalities after transfusion. Hemolysis during IAT collection can lead to hemoglobinuria and binding of nitric oxide, leading to vasoconstriction. The literature suggests that stroma from damaged cells and contact of the blood with the IAT device can lead to coagulation abnormalities and other morbidities, including adult respiratory distress syndrome. |
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Authors:
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Tod B Sloan; Greg Myers; Daniel J Janik; Evalina M Burger; Vikas V Patel; Leslie C Jameson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 109 ISSN: 1526-7598 ISO Abbreviation: Anesth. Analg. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-18 Completed Date: 2009-07-21 Revised Date: 2009-10-23 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
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Languages: eng Pagination: 38-42 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology, University of Colorado at Denver and Health Sciences Center, Anschutz Office West (AO1), PO Box 6511, 12631 E 17th Ave., Aurora, CO 80045, USA. tod.sloan@ucdenver.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Loss, Surgical
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prevention & control Blood Transfusion, Autologous / methods* Female Hemolysis* / physiology Humans Intraoperative Care / methods* Male Middle Aged |
| Comments/Corrections | |
Comment In:
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Anesth Analg. 2009 Nov;109(5):1706; author reply 1706-7
[PMID:
19843818
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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