Document Detail


Intraoperative assessment of nodal staging at thoracotomy for carcinoma of the bronchus.
MedLine Citation:
PMID:  2185799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the staging of operable carcinoma of the bronchus, accurate assessment of mediastinal nodal status is essential in order to determine the feasibility and desirability of resection. In the UK, frozen section analysis is often logistically difficult, and many surgeons rely upon naked-eye assessment. To evaluate the accuracy of this approach, we have reviewed 100 thoracotomies performed for cancer in this unit and compared the naked-eye assessment of nodal staging with the ultimate histological findings. A total of 287 lymph nodes were examined. There were 14 false positives and 10 false negatives. The overall accuracy of naked-eye assessment was 96.1%. On no occasion did an error in naked-eye assessment result in a patient receiving inappropriate treatment. All patients were thought to be pTNM N0 or N1 prior to surgery, yet N2 disease was established in 24 patients. The value of routine mediastinal node dissection at the time of thoracotomy has been established and an important subgroup of patients with microscopic N2 disease has been identified.
Authors:
J A Gaer; P Goldstraw
Related Documents :
16970289 - Is routine mediastinoscopy indicated for patients with t1 non-small cell lung cancer?
11594519 - Primary mediastinal large b-cell lymphoma: a comparative study with nodular sclerosis-t...
20709359 - Primary angiosarcomas of the anterior mediastinum: a clinicopathologic and immunohistoc...
23115789 - The features of late local recurrences following curative surgery for rectal cancer.
1728219 - Repeat mediastinoscopy in the assessment of new and recurrent lung neoplasm.
21969509 - Randomized, double-blind, placebo-controlled phase ii study of single-agent oral talact...
20427349 - Survival differences among women with de novo stage iv and relapsed breast cancer.
18096209 - Outcome after combined modality treatment for uterine papillary serous carcinoma: a stu...
20393019 - Pattern of failure following chemoradiation for locally advanced non-small cell lung ca...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  4     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  1990  
Date Detail:
Created Date:  1990-06-13     Completed Date:  1990-06-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  207-10     Citation Subset:  IM    
Affiliation:
Brompton Hospital, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Bronchial Neoplasms / pathology,  surgery*
Carcinoma / pathology,  surgery
Carcinoma, Squamous Cell / pathology,  surgery*
Humans
Intraoperative Period
Lymph Nodes / pathology*,  surgery
Mediastinum
Retrospective Studies
Sensitivity and Specificity
Thoracotomy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Myocardial perfusion studies by contrast echocardiography.
Next Document:  Transesophageal sonography in central bronchial carcinoma.