Document Detail

Intraocular pressure reduction induced by hornet venom in the normal eye.
MedLine Citation:
PMID:  6126099     Owner:  NLM     Status:  MEDLINE    
Intravenous injection into rabbits and cats of an aqueous extract of hornet venom sac, produced a significant reduction in the intraocular pressure. The mean reduction of the ocular pressure was between 7 and 15 mm Hg within one hour past injection and it lasted 6-12 h or in several instances even more than 24 h. The effect is produced by some thermolabile high-molecular-weight fraction(s), is dose-dependent and is reproducible by repetitive injections. Side effects may include diarrhea, micturition and lethargy, but usually there is no marked effect on the size of the pupil.
J S Ishay; M E Yalon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta tropica     Volume:  39     ISSN:  0001-706X     ISO Abbreviation:  Acta Trop.     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-10-12     Completed Date:  1982-10-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370374     Medline TA:  Acta Trop     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  171-8     Citation Subset:  IM    
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MeSH Terms
Bee Venoms / pharmacology*
Dose-Response Relationship, Drug
Intraocular Pressure*
Time Factors
Wasp Venoms / pharmacology*
Reg. No./Substance:
0/Bee Venoms; 0/Wasp Venoms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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