Document Detail


Intraocular pressure changes and postural changes of intraocular pressure in experimentally induced Hansen's disease of rhesus, mangabey, and African green monkeys.
MedLine Citation:
PMID:  2223699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In our long term evaluation of patients with Hansen's disease we have frequently found reduction of their intraocular pressure. Furthermore, we noted changes in their intraocular pressure on change of posture. To determine if these changes have any significance we measured the intraocular pressures of 24 experimentally infected and 39 control monkeys in both sitting and reclining positions. We found significant reduction of intraocular pressure in 66.7% compared with controls in the sitting position, and a significant increase in intraocular pressure in 79% when checked first in the sitting then in the reclining position. We offer a possible pathophysiological explanation as to why the changes occur.
Authors:
N Hussein; B Ostler; B J Gormus; R Wolf; G P Walsh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  74     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1990-12-14     Completed Date:  1990-12-14     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  647-9     Citation Subset:  IM    
Affiliation:
Francis I Proctor Foundation, University of California, San Francisco 94143.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cercopithecidae
Cercopithecus aethiops
Female
Intraocular Pressure / physiology*
Leprosy / physiopathology*
Macaca mulatta
Male
Posture*
Comments/Corrections

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