Document Detail

Intraocular pressure and associated factors: the central India eye and medical study.
MedLine Citation:
PMID:  21897285     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To determine the range of intraocular pressure (IOP) in a rural Central Indian population and to evaluate existing and identify potential new ocular, medical, and socioeconomic factors associated with IOP.
METHODS: This is a population-based study carried out in Nagpur in Central India. A single IOP measurement was taken using Goldmann applanation tonometry and population IOP was described using standard descriptive statistics.
RESULTS: Of 5885 eligible patients, 9338 eyes of 4686 patients were included in the study. The mean IOP was 13.6±3.4 mm Hg (median: 14 mm Hg; range: 2 to 56 mm Hg). In multivariate regression analysis, the following factors, with correlation coefficients (r) and P values reported in parenthesis, were found to be associated with IOP. Ocular factors included higher corneal power (0.12; P=0.004), lower central corneal thickness (0.02; P<0.001), and higher myopic refractive power (-0.13; P=0.001). Medical factors included diastolic blood pressure (0.05; P<0.001), pulse rate (0.02; P=0.005), and body mass index (0.05; P=0.01). Socioeconomic factors included level of education (0.15; P=0.05) and livestock ownership (-0.18; P=0.008).
CONCLUSION: Low mean IOP was found when compared with other epidemiologic studies and this may be explained by the low central corneal thickness found in the study population. Several known ocular and medical factors and new socioeconomic factors were found to be associated with IOP. Identifying risk factors associated with IOP in different populations may allow clinicians to better define and recognize subgroups of patients at risk of elevated IOP. Newly identified socioeconomic-IOP associations will need to be validated in future studies.
Jost B Jonas; Vinay Nangia; Arshia Matin; Ajit Sinha; Maithili Kulkarni; Krishna Bhojwani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of glaucoma     Volume:  20     ISSN:  1536-481X     ISO Abbreviation:  J. Glaucoma     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9300903     Medline TA:  J Glaucoma     Country:  United States    
Other Details:
Languages:  eng     Pagination:  405-9     Citation Subset:  IM    
*Suraj Eye Institute, Nagpur, Maharashtra, India †Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University, Heidelberg, Mannheim, Germany.
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