| Intraocular pressure after cataract surgery using Provasc, Viscoat either separately or in combination. | |
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MedLine Citation:
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PMID: 19149126 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare the intraocular pressure values after small-incision cataract surgery using either Provisc or Viscoat, separately or in combination. DESIGN: Prospective, randomized and masked clinical study. PARTICIPANTS: 147 eyes of 147 consecutive cataract patients. METHODS: The patients were randomly assigned to receive either Provisc (P group), Viscoat (V group) or both (V+P group) and intraocular pressure was measured at 1, 2, 3, 6, 9 and 24 h after surgery. RESULTS: There were no statistically significant differences in intraocular pressure between the P and V+P group at any point in time during the follow-up period (p>0.05); however, in the V group the intraocular pressure was higher than in the other 2 groups at 1 h (p=0.005 and p=0.006 respectively) and 2 h (p<0.001 and p<0.001 respectively). In the V group, intraocular pressure was also higher than the P group at 3 h (p<0.001). Over 50% of patients from the V group had intraocular pressure values of 30 mmHg and over after 2 h and 3 h from surgery. There were no statistically significant differences between the study groups concerning the intraocular pressure values measured at 6 h, 9 h and 24 h postoperatively (p>0.05). CONCLUSIONS: Viscoat results more frequently in high intraocular pressure values during the initial 6 h after small-incision cataract surgery with frequent cases in which the intraocular pressure could increase over 30 mmHg; therefore, close follow-up of these patients is necessary. |
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Authors:
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D Chiseliţă; C Danielescu; Doina Gherghel |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Oftalmologia (Bucharest, Romania : 1990) Volume: 52 ISSN: 1220-0875 ISO Abbreviation: Oftalmologia Publication Date: 2008 |
Date Detail:
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Created Date: 2009-01-19 Completed Date: 2009-03-05 Revised Date: 2010-10-25 |
Medline Journal Info:
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Nlm Unique ID: 9111247 Medline TA: Oftalmologia Country: Romania |
Other Details:
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Languages: eng Pagination: 91-7 Citation Subset: IM |
Affiliation:
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Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Algorithms Analysis of Variance Cataract Extraction / methods Chondroitin / administration & dosage* Chondroitin Sulfates / administration & dosage* Double-Blind Method Drug Combinations Female Humans Hyaluronic Acid / administration & dosage* Intraocular Pressure / drug effects* Lens Implantation, Intraocular Male Middle Aged Phacoemulsification / methods* Postoperative Period Prospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 0/chondroitin sulfate, sodium hyaluronate drug combination; 9004-61-9/Hyaluronic Acid; 9007-27-6/Chondroitin; 9007-28-7/Chondroitin Sulfates |
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