Document Detail

Intraocular pressure after cataract surgery using Provasc, Viscoat either separately or in combination.
MedLine Citation:
PMID:  19149126     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare the intraocular pressure values after small-incision cataract surgery using either Provisc or Viscoat, separately or in combination. DESIGN: Prospective, randomized and masked clinical study. PARTICIPANTS: 147 eyes of 147 consecutive cataract patients. METHODS: The patients were randomly assigned to receive either Provisc (P group), Viscoat (V group) or both (V+P group) and intraocular pressure was measured at 1, 2, 3, 6, 9 and 24 h after surgery. RESULTS: There were no statistically significant differences in intraocular pressure between the P and V+P group at any point in time during the follow-up period (p>0.05); however, in the V group the intraocular pressure was higher than in the other 2 groups at 1 h (p=0.005 and p=0.006 respectively) and 2 h (p<0.001 and p<0.001 respectively). In the V group, intraocular pressure was also higher than the P group at 3 h (p<0.001). Over 50% of patients from the V group had intraocular pressure values of 30 mmHg and over after 2 h and 3 h from surgery. There were no statistically significant differences between the study groups concerning the intraocular pressure values measured at 6 h, 9 h and 24 h postoperatively (p>0.05). CONCLUSIONS: Viscoat results more frequently in high intraocular pressure values during the initial 6 h after small-incision cataract surgery with frequent cases in which the intraocular pressure could increase over 30 mmHg; therefore, close follow-up of these patients is necessary.
D Chiseliţă; C Danielescu; Doina Gherghel
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Oftalmologia (Bucharest, Romania : 1990)     Volume:  52     ISSN:  1220-0875     ISO Abbreviation:  Oftalmologia     Publication Date:  2008  
Date Detail:
Created Date:  2009-01-19     Completed Date:  2009-03-05     Revised Date:  2010-10-25    
Medline Journal Info:
Nlm Unique ID:  9111247     Medline TA:  Oftalmologia     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  91-7     Citation Subset:  IM    
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
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MeSH Terms
Analysis of Variance
Cataract Extraction / methods
Chondroitin / administration & dosage*
Chondroitin Sulfates / administration & dosage*
Double-Blind Method
Drug Combinations
Hyaluronic Acid / administration & dosage*
Intraocular Pressure / drug effects*
Lens Implantation, Intraocular
Middle Aged
Phacoemulsification / methods*
Postoperative Period
Prospective Studies
Treatment Outcome
Reg. No./Substance:
0/Drug Combinations; 0/chondroitin sulfate, sodium hyaluronate drug combination; 9004-61-9/Hyaluronic Acid; 9007-27-6/Chondroitin; 9007-28-7/Chondroitin Sulfates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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