Document Detail


Intraocular pressure and related systemic and ocular biometric factors in a population-based study in Japan: the Kumejima study.
MedLine Citation:
PMID:  20570236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To examine the distribution of intraocular pressure (IOP) and its related systemic and ocular biometric factors in a population-based study in a southwestern island of Japan. DESIGN: Cross-sectional, population-based study. METHODS: All residents of Kumejima Island, Japan, located in southwestern Japan (eastern longitude, 126 degrees 48 minutes and northern latitude 26 degrees 20 minutes), 40 years of age and older were asked to undergo a comprehensive questionnaire and ocular examination, including measurement of IOP with Goldmann applanation tonometry. RESULTS: Of the 4632 eligible residents, 3762 (81.2%) underwent the examination. In 2838 non-glaucomatous subjects from whom reliable measurements of IOP were obtained, the mean IOPs +/- standard deviation in all, men, and women were 15.1 +/- 3.1 mm Hg (n = 2838), 15.2 +/- 3.1 mm Hg (n = 1450), and 15.1 +/- 3.0 mm Hg (n = 1388), respectively, with no significant intersex difference (P = .63). Multivariate regression analysis demonstrated that higher IOP was significantly correlated with younger age (P < .001), higher body mass index (P < .001), higher systolic blood pressure (P < .001), history of diabetes mellitus (P = .001), thicker central corneal thickness (P < .001), steeper corneal curvature (P < .001), and longer axial length (P < .018), but not with anterior chamber depth and the Shaffer angle width grade. CONCLUSIONS: Younger age, higher body mass index, higher systolic blood pressure, diabetes, thicker central corneal thickness, and steeper corneal curvature were significantly correlated with higher IOP. The present results confirm that IOP is associated with systemic and ocular biometric factors and may define specific subgroups most likely to have an elevated IOP.
Authors:
Eriko Tomoyose; Akiko Higa; Hiroshi Sakai; Shoichi Sawaguchi; Aiko Iwase; Atsuo Tomidokoro; Shiro Amano; Makoto Araie
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-08
Journal Detail:
Title:  American journal of ophthalmology     Volume:  150     ISSN:  1879-1891     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  279-86     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Biometry
Blood Pressure / physiology
Body Mass Index
Cross-Sectional Studies
Diabetes Complications
Epidemiologic Studies
Female
Glaucoma / epidemiology
Gonioscopy
Humans
Intraocular Pressure / physiology*
Japan / epidemiology
Male
Middle Aged
Ophthalmoscopy
Questionnaires
Reference Values
Risk Factors
Tonometry, Ocular

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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