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Intraocular Pressure Following Combined Routes of Bevacizumab-augmented Trabeculectomy for Refractory Neovascular Glaucoma.
MedLine Citation:
PMID:  23448559     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
ABSTRACT Purpose: To evaluate the intraocular pressure (IOP) control following combined routes of adjuvant bevacizumab with trabeculectomy in refractory neovascular glaucoma. Methods: From June 2011 to December 2011, 5 consecutive cases of neovascular glaucoma with persistent raised IOP on maximal medical treatment underwent adjuvant bevacizumab by combined routes (subconjunctival (SC) and/or intracameral (IC), intravitreal (IV) injections) before pan-retinal photocoagulation (PRP). Needs for repeat procedures or medications for IOP control over the postoperative period were assessed. Results: The mean IOP (1 SC, 1 IC + IV, 3 SC + IC routes) reduced from 40 ± 5.5 mm Hg to 17 ± 3.7 mm Hg at a mean final follow-up of 4 ± 3.7months (range 1-9 months), respectively (p < 0.001 for each). All eyes had transient IOP spikes 1-3 months after surgery, which normalized spontaneously after PRP, while one eye required topical medications for IOP control. Conclusions: Combined routes of adjuvant bevacizumab augmented trabeculectomy may help in better IOP control (IC + IV > IC + SC > SC) in refractory neovascular glaucoma but require additional procedures for sustained effect.
Authors:
Susanta Chatterjee; Aparna Rao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in ophthalmology     Volume:  28     ISSN:  1744-5205     ISO Abbreviation:  Semin Ophthalmol     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610759     Medline TA:  Semin Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  72-4     Citation Subset:  IM    
Affiliation:
LV Prasad Eye Institute , Bhubaneswar, Odhisha , India.
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