Document Detail

Intraneural perineurioma of the sciatic nerve in early childhood.
MedLine Citation:
PMID:  19520281     Owner:  NLM     Status:  MEDLINE    
Intraneural perineurioma is an uncommon benign neoplasm characterized by focal perineural cell proliferation. The typical course is indolent, with gradual onset and slow progression of motor loss. In early childhood, uncertainty concerning the time of onset can lead to difficulty in distinguishing this potential treatable lesion from congenital and other causes of nerve palsy. In the present case, clinical presentation, electrophysiologic findings, and magnetic resonance imaging findings in a child were compatible with intraneural perineurioma of the lumbosacral trunk and sciatic nerve. Initially, peroneal neuropathy was suspected. The case illustrates that sciatic intraneural perineuriomas do occur in early childhood, and that traction on the sciatic nerve may result in earlier damage to the peroneal nerve than to the tibial nerve, thus mimicking a more peripheral lesion.
John R Østergaard; Torben Smith; Brian Stausbøl-Grøn
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  41     ISSN:  1873-5150     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-12     Completed Date:  2009-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  68-70     Citation Subset:  IM    
Center for Rare Diseases, Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark.
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MeSH Terms
Child, Preschool
Diagnosis, Differential
Magnetic Resonance Imaging
Muscle, Skeletal / pathology,  physiopathology
Nerve Sheath Neoplasms / diagnosis*,  pathology
Pelvis / pathology
Peroneal Neuropathies / diagnosis
Sciatic Neuropathy / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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