Document Detail

Intranasal clonidine as a premedicant: three cases with unique indications.
MedLine Citation:
PMID:  18095969     Owner:  NLM     Status:  MEDLINE    
Clonidine is experiencing increasing use in the pediatric population as a sedative and analgesic because of its central alpha2-adrenergic agonism. We report three cases of preoperative use of intranasal clonidine in pediatric patients, all for different indications. One patient was treated for preoperative agitation and hallucinations associated with oral midazolam. One patient was given clonidine as a premedicant. The third patient was treated for preoperative agitation and hypertension. All three patients had subjective resolution of indicated symptoms and none experienced adverse outcomes.
Michael J Stella; Ann G Bailey
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  18     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-21     Completed Date:  2008-03-31     Revised Date:  2008-11-04    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  France    
Other Details:
Languages:  eng     Pagination:  71-3     Citation Subset:  IM    
Department of Anesthesiology, University of North Carolina Hospitals, Chapel Hill, NC 27599-7010, USA.
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MeSH Terms
Administration, Intranasal
Adrenergic alpha-Agonists* / administration & dosage,  adverse effects
Asthma / complications
Attention Deficit Disorder with Hyperactivity / complications
Balloon Dilatation
Blood Platelet Disorders / complications
Child, Preschool
Clonidine* / administration & dosage,  adverse effects
Epidermolysis Bullosa / complications
Esophagus / surgery
Hallucinations / chemically induced
Mouth Rehabilitation
Urethra / abnormalities,  surgery
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 4205-90-7/Clonidine
Comment In:
Paediatr Anaesth. 2008 Aug;18(8):800   [PMID:  18613939 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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