| Intramuscular NSAIDS reduce post-operative pain after minor outpatient anaesthesia. | |
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MedLine Citation:
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PMID: 8829939 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two hundred healthy patients scheduled for elective minor gynaecological surgery under general anaesthesia were randomly allocated to one of four groups who received either diclofenac 75 mg intramuscularly (i.m.), ketorolac 30 mg i.m., diclofenac 50 mg orally, or 2 mL NaCl i.m. The drugs were administered 10-20 min prior to a standard anaesthetic. All surgery was uneventful. The patients were discharged after a mean of 110 +/- 30 min with no differences between the groups. Complaints about pain and need for post-operative analgesics were significantly less frequent in the two groups of patients receiving an intramuscular non-steroidal anti-inflammatory drug (NSAID), as compared to placebo. The patients who received 50 mg diclofenac orally, administered shortly before the procedure, had the same pain course as the placebo patients. |
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Authors:
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J Jakobsson; K Rane; S Davidson |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: European journal of anaesthesiology Volume: 13 ISSN: 0265-0215 ISO Abbreviation: Eur J Anaesthesiol Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1996-10-17 Completed Date: 1996-10-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8411711 Medline TA: Eur J Anaesthesiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 67-71 Citation Subset: IM |
Affiliation:
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Department of Anaesthesia, Karolinska Institute at Danderyds Hospital, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adult Ambulatory Surgical Procedures Anti-Inflammatory Agents, Non-Steroidal / administration & dosage* Diclofenac / administration & dosage* Double-Blind Method Humans Injections, Intramuscular Ketorolac Pain, Postoperative / drug therapy* Tolmetin / administration & dosage, analogs & derivatives* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 15307-86-5/Diclofenac; 26171-23-3/Tolmetin; 66635-83-4/Ketorolac |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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