Document Detail

Intramuscular NSAIDS reduce post-operative pain after minor outpatient anaesthesia.
MedLine Citation:
PMID:  8829939     Owner:  NLM     Status:  MEDLINE    
Two hundred healthy patients scheduled for elective minor gynaecological surgery under general anaesthesia were randomly allocated to one of four groups who received either diclofenac 75 mg intramuscularly (i.m.), ketorolac 30 mg i.m., diclofenac 50 mg orally, or 2 mL NaCl i.m. The drugs were administered 10-20 min prior to a standard anaesthetic. All surgery was uneventful. The patients were discharged after a mean of 110 +/- 30 min with no differences between the groups. Complaints about pain and need for post-operative analgesics were significantly less frequent in the two groups of patients receiving an intramuscular non-steroidal anti-inflammatory drug (NSAID), as compared to placebo. The patients who received 50 mg diclofenac orally, administered shortly before the procedure, had the same pain course as the placebo patients.
J Jakobsson; K Rane; S Davidson
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  13     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-10-17     Completed Date:  1996-10-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  67-71     Citation Subset:  IM    
Department of Anaesthesia, Karolinska Institute at Danderyds Hospital, Sweden.
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MeSH Terms
Administration, Oral
Ambulatory Surgical Procedures
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
Diclofenac / administration & dosage*
Double-Blind Method
Injections, Intramuscular
Pain, Postoperative / drug therapy*
Tolmetin / administration & dosage,  analogs & derivatives*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 15307-86-5/Diclofenac; 26171-23-3/Tolmetin; 66635-83-4/Ketorolac

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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