Document Detail

Intramural Idiopathic Ventricular Arrhythmias Originating in the Intra-ventricular Septum: Mapping and Ablation.
MedLine Citation:
PMID:  22407415     Owner:  NLM     Status:  Publisher    
BACKGROUND: -Intramural septal idiopathic ventricular arrhythmias have not been described systematically. METHODS AND RESULTS: -In a consecutive group of 93 patients with idiopathic ventricular arrhythmias referred for ablation, the site of origin of ventricular arrhythmias was assessed by activation mapping and pace-mapping. In 7/93 patients (8%), an intramural focus in the inter-ventricular septum was identified. All ventricular arrhythmias arising intramurally had a left bundle branch block morphology with inferior axis. The intramural focus was effectively ablated from both sides of the septum in 4 patients, and from within the septum in 1 patient. The ablation procedure of an intramural focus near the His bundle failed in 2/7 patients. Electrocardiogram and mapping characteristics of the patients with intramural septal ventricular arrhythmias differentiated intramural arrhythmias from other sites of origin. CONCLUSIONS: -Idiopathic septal ventricular arrhythmias can originate from intramural foci. Activation mapping from within a perforator branch within the inter-ventricular septum is helpful in identifying the site of origin of intramural septal arrhythmias. Ablation within the septum or from both sites of the septum may be required to eliminate the targeted arrhythmia.
Miki Yokokawa; Eric Good; Aman Chugh; Frank Pelosi; Thomas Crawford; Krit Jongnarangsing; Rakesh Latchamsetty; Hakan Oral; Fred Morady; Frank Bogun
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-9
Journal Detail:
Title:  Circulation. Arrhythmia and electrophysiology     Volume:  -     ISSN:  1941-3084     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101474365     Medline TA:  Circ Arrhythm Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
University of Michigan, Ann Arbor, MI.
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