Document Detail

Intramolecular vinylsilane-oxocarbenium condensations: concise assembly of cis-bicyclic ether arrays.
MedLine Citation:
PMID:  17676858     Owner:  NLM     Status:  MEDLINE    
Lewis acid-mediated intramolecular attack of vinylsilanes at tethered oxonium precursors 1 results in a rapid assembly of the cis-fused bicyclic ether species 3, with complete regio- and stereospecific control, and in some cases near-quantitative yield. Continued investigation suggests a general approach to a variety of such ether frameworks.
Stephen Philip Fearnley; Pedro Lory
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-08-04
Journal Detail:
Title:  Organic letters     Volume:  9     ISSN:  1523-7060     ISO Abbreviation:  Org. Lett.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-23     Completed Date:  2007-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3507-10     Citation Subset:  IM    
Department of Chemistry & Physics, Lamar University, P.O. Box 10022, Beaumont, Texas 77710, USA.
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MeSH Terms
Bicyclo Compounds / chemical synthesis*,  chemistry
Ethers, Cyclic / chemical synthesis*,  chemistry
Molecular Structure
Oxygen / chemistry
Silanes / chemistry*
Vinyl Compounds / chemistry*
Reg. No./Substance:
0/Bicyclo Compounds; 0/Ethers, Cyclic; 0/Silanes; 0/Vinyl Compounds; 0/vinylsilane; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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