Document Detail


Intramolecular hydroamination of dithioketene acetals: an easy route to cyclic amino acid derivatives.
MedLine Citation:
PMID:  20945849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Catalytic intramolecular hydroamination of dithioketene acetals was developed for the synthesis of cyclic amino acid derivatives. Triggered by the addition of a catalytical amount of n-BuLi, the reaction proceeds to give proline and pipecolic acid derivatives in excellent yields and diastereoselectivity.
Authors:
Hai-Chao Xu; Kevin D Moeller
Related Documents :
8216379 - 5-benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphor...
3121479 - Antimicrobial properties of aromatic compounds of plant origin.
17158669 - Arylamine n-acetyltransferase responsible for acetylation of 2-aminophenols in streptom...
11526019 - Novel ring cleavage products in the biotransformation of biphenyl by the yeast trichosp...
18328679 - Critical micellar concentrations of keto derivatives of selected bile acids: thermodyna...
23762859 - Mechanisms of omega-3 polyunsaturated fatty acids in prostate cancer prevention.
3941109 - Atp- and coenzyme a-dependent fatty acid incorporation into proteins of cell-free extra...
18348529 - Isolation and structure elucidation of antioxidant polyphenols from quince (cydonia vul...
2590189 - The transport of l-arginine in chinese hamster ovary cells.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-10-14
Journal Detail:
Title:  Organic letters     Volume:  12     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-12     Completed Date:  2011-01-14     Revised Date:  2014-04-23    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5174-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acetals / chemistry
Amination
Amino Acids, Cyclic / chemical synthesis*,  chemistry
Catalysis
Combinatorial Chemistry Techniques
Organometallic Compounds / chemistry
Pipecolic Acids / chemical synthesis*,  chemistry
Proline / analogs & derivatives,  chemical synthesis*
Stereoisomerism
Grant Support
ID/Acronym/Agency:
P41 GM103422/GM/NIGMS NIH HHS; P41 RR000954/RR/NCRR NIH HHS; RR00954/RR/NCRR NIH HHS; RR02004/RR/NCRR NIH HHS; RR05018/RR/NCRR NIH HHS; RR07155/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Acetals; 0/Amino Acids, Cyclic; 0/Organometallic Compounds; 0/Pipecolic Acids; 0/n-butyllithium; 535-75-1/pipecolic acid; 9DLQ4CIU6V/Proline
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Raman scattering at pure graphene zigzag edges.
Next Document:  Catalytic acylation of amines with aldehydes or aldoximes.