| Intramedullary tuberculosis manifested as Brown-Sequard syndrome in a patient with systemic lupus erythematosus. | |
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MedLine Citation:
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PMID: 10787014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 25-year-old girl presented with progressive deterioration of right side weakness with decreased sensation on the left trunk. She had been treated with high dose steroid due to autoimmune thrombocytopenia for 2 months. Clinical, laboratory and immunologic studies revealed that she had systemic lupus erythematosus (SLE), MRI of spinal cord showed marginal contrast enhancing and fluid containing mass in the cord of the C5-6 level, suggesting intramedullary abscess. She underwent surgery of mass removal with biopsy. The pathologic findings from cord tissues revealed numerous acid fast bacilli (AFB) in necrotic tissues. After surgery and anti-tuberculous treatment, her neurologic symptoms were markedly improved with restoration of right side motor weakness. To our knowledge, this is the first case report of intramedullary tuberculosis in a patient with SLE. Since intramedullary tuberculosis may sometimes mimic neurologic complication of SLE itself, it may pose diagnostic and therapeutic confusion for clinicians. We report a case of spinal cord tuberculosis affecting C5, 6 level which was manifested as Brown-Sequard syndrome in a patient with SLE. |
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Authors:
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W U Kim; S H Lee; B Y Shim; J K Min; Y S Hong; S H Park; C S Cho; C K Park; H Y Kim |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lupus Volume: 9 ISSN: 0961-2033 ISO Abbreviation: Lupus Publication Date: 2000 |
Date Detail:
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Created Date: 2000-06-08 Completed Date: 2000-06-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9204265 Medline TA: Lupus Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 147-50 Citation Subset: IM |
Affiliation:
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Research Center in Catholic Medical Center, Kang-Nam St. Mary's Hospital, Department of Internal Medicine, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Brown-Sequard Syndrome / diagnosis* Diagnosis, Differential Female Humans Lupus Erythematosus, Systemic / complications*, diagnosis* Magnetic Resonance Imaging Purpura, Thrombocytopenic, Idiopathic / drug therapy Spinal Cord / pathology Steroids / therapeutic use Tuberculosis, Spinal / complications*, diagnosis*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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