Document Detail

Intramedullary tuberculosis manifested as Brown-Sequard syndrome in a patient with systemic lupus erythematosus.
MedLine Citation:
PMID:  10787014     Owner:  NLM     Status:  MEDLINE    
A 25-year-old girl presented with progressive deterioration of right side weakness with decreased sensation on the left trunk. She had been treated with high dose steroid due to autoimmune thrombocytopenia for 2 months. Clinical, laboratory and immunologic studies revealed that she had systemic lupus erythematosus (SLE), MRI of spinal cord showed marginal contrast enhancing and fluid containing mass in the cord of the C5-6 level, suggesting intramedullary abscess. She underwent surgery of mass removal with biopsy. The pathologic findings from cord tissues revealed numerous acid fast bacilli (AFB) in necrotic tissues. After surgery and anti-tuberculous treatment, her neurologic symptoms were markedly improved with restoration of right side motor weakness. To our knowledge, this is the first case report of intramedullary tuberculosis in a patient with SLE. Since intramedullary tuberculosis may sometimes mimic neurologic complication of SLE itself, it may pose diagnostic and therapeutic confusion for clinicians. We report a case of spinal cord tuberculosis affecting C5, 6 level which was manifested as Brown-Sequard syndrome in a patient with SLE.
W U Kim; S H Lee; B Y Shim; J K Min; Y S Hong; S H Park; C S Cho; C K Park; H Y Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lupus     Volume:  9     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  2000  
Date Detail:
Created Date:  2000-06-08     Completed Date:  2000-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  147-50     Citation Subset:  IM    
Research Center in Catholic Medical Center, Kang-Nam St. Mary's Hospital, Department of Internal Medicine, Seoul, Korea.
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MeSH Terms
Brown-Sequard Syndrome / diagnosis*
Diagnosis, Differential
Lupus Erythematosus, Systemic / complications*,  diagnosis*
Magnetic Resonance Imaging
Purpura, Thrombocytopenic, Idiopathic / drug therapy
Spinal Cord / pathology
Steroids / therapeutic use
Tuberculosis, Spinal / complications*,  diagnosis*,  pathology
Reg. No./Substance:

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