| Intramedullary spinal cord metastases: review of the literature. | |
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MedLine Citation:
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PMID: 20668492 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To review the epidemiology, dissemination, clinical presentation, diagnosis, treatment, survival and functional outcome of intramedullary spinal cord metastases (ISCM). METHODS: Literature review of all surgically treated cases of ISCM and all described cases of ISCM of breast carcinoma. RESULTS: 42 references to 87 surgically treated cases of ISCM were found, 13 references to 27 cases with diagnosed and treated ISCM of breast carcinoma. In only 9 cases of spinal cord metastases of breast cancer was surgical resection of ISCM done (10% of all surgically treated ISCM). CONCLUSIONS: Three treatment modalities are available for ISCM: radiotherapy, chemotherapy, and surgery. The gold standard remains radiotherapy. Microsurgical resection of a focal intramedullary mass appears to be feasible and should be considered in selected cases. Patients who have no evidence of widespread organ metastases or multiple intramedullary lesions and who have a life expectancy of at least a few months with tumours of non-lymphoma histology should be considered for tumor resection. In conclusion, ISCM are difficult to treat lesions, but early diagnosis, careful surgical management and maintenance therapy may substantially contribute to a satisfactory functional outcome and prolonged survival. |
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Authors:
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Lumir Hrabalek |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia Volume: 154 ISSN: 1213-8118 ISO Abbreviation: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-29 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101140142 Medline TA: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Country: Czech Republic |
Other Details:
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Languages: eng Pagination: 117-22 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Palacky University and University Hospital Olomouc. lumir.hrabalek@seznam.cz |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Spinal Cord Neoplasms / diagnosis, secondary*, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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