Document Detail

Intralobar pulmonary sequestration presenting increased serum CA19-9 and CA125.
MedLine Citation:
PMID:  12413014     Owner:  NLM     Status:  MEDLINE    
A 39-year-old man was admitted to our hospital for further evaluation of a consolidated shadow and clarification of the cause of serum tumor marker elevation (CA19-9 496.2 U/ml, CA125 160.6 U/ml). Chest computed tomography revealed a well-defined homogeneous nodule in the left S(10). Angiography showed one aberrant artery, branching from the ascending aorta. Intralobar pulmonary sequestration was diagnosed and the sequestrated lung was resected. Microscopic findings of the sequestrated lung showed a mucus-containing cystically dilated bronchus, which was covered with ciliated cylindrical epithelium. Immunohistochemical staining showed positive staining for CA19-9 and CA125 in both the ciliated cylindrical epithelium and mucus. Serum values of tumor markers returned to their normal range after surgery.
Hisanaga Yagyu; Hideki Adachi; Kinya Furukawa; Hiroyuki Nakamura; Akihiko Sudoh; Shuuji Oh-ishi; Fumihiro Tsuchida; Kouji Kishi; Makoto Saitou; Takeshi Matsuoka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  41     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2003-04-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  875-8     Citation Subset:  IM    
Fifth Department of Internal Medicine, Tokyo Medical University, Inashiki-gun, Ibaraki.
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MeSH Terms
Bronchopulmonary Sequestration / blood*,  radiography*,  surgery
CA-125 Antigen / blood*
CA-19-9 Antigen / blood*
Lung / pathology,  radiography,  surgery
Pulmonary Surgical Procedures / methods
Radiography, Thoracic
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/CA-125 Antigen; 0/CA-19-9 Antigen

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