| Intralesional interferon alfa-2b treatment of keratoacanthomas. | |
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MedLine Citation:
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PMID: 15577764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Complete excision is not always easy when a keratoacanthoma is large or located in certain anatomic areas. An effective nonsurgical treatment would be desirable in such cases. OBJECTIVE: This was a pilot study of the effects of intralesional interferon alfa-2b in the treatment of rapidly growing keratoacanthomas. METHODS: A total of 4 large, rapidly growing keratoacanthomas, which were located on the lower lip, neck, and cheeks of the 4 different patients, were treated with intralesional interferon alfa-2b injection weekly. Serial photographs were taken to observe the course of responses. RESULTS: All lesions resolved completely in 5 to 7 weeks with acceptable cosmetic results. CONCLUSION: Intralesional interferon alfa-2b can be a treatment modality of these difficult lesions. |
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Authors:
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Chang-Keun Oh; Hyo-Sung Son; Jae-Bong Lee; Ho-Sun Jang; Kyung-Sool Kwon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 51 ISSN: 1097-6787 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-12-03 Completed Date: 2005-03-25 Revised Date: 2005-06-24 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: S177-80 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Pusan National University College of Medicine, Busan, Korea. ckoh@pusan.ac.kr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cheek* Chills / chemically induced Female Fever / chemically induced Follow-Up Studies Humans Injections, Intralesional / adverse effects Interferon Alfa-2b / administration & dosage*, adverse effects Keratoacanthoma / drug therapy* Lip Diseases / drug therapy* Male Middle Aged Neck* Pain / etiology Pilot Projects |
| Chemical | |
Reg. No./Substance:
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99210-65-8/Interferon Alfa-2b |
| Comments/Corrections | |
Erratum In:
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J Am Acad Dermatol. 2004 Dec;51(6):1040 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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