Document Detail

Intralesional curettage, with phenol and cement as adjuvants, for low-grade intramedullary chondrosarcoma of the long bones.
MedLine Citation:
PMID:  22187844     Owner:  NLM     Status:  In-Process    
The authors conducted a retrospective study on 23 patients (12 females and 11 males) with low-grade intramedullary chondrosarcoma of a long bone, treated with intralesional curettage, phenolization and cementation. The use of phenol was supported by an in vitro study, the use of bone cement by clinical studies. A consensus has been growing that this type of tumours should be treated less aggressively. The average age of the patients was 445 years (range: 29 to 71). The mean follow-up period was 6.2 years (range: 2.5 to 11 years). After 6 months the average Musculoskeletal Tumor Society (MSTS) score was 76.8% of 30, the best possible score (range: 61% to 87%). After 12 months this score increased to 89.8% (range: 63% to 100%). Complications were: one recurrence (43%), treated with a tumour prosthesis, and 3 fractures (13%). The authors strongly support this new technique, all the more as it still allows for a more radical approach, if necessary. They stress the importance of a strict follow-up by a multidisciplinary team, in order to treat local recurrences and (rarely) metastases.
Luigi Di Giorgio; Georgios Touloupakis; Fabrizio Vitullo; Luca Sodano; Marco Mastantuono; Ciro Villani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta orthopaedica Belgica     Volume:  77     ISSN:  0001-6462     ISO Abbreviation:  Acta Orthop Belg     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-12-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985165R     Medline TA:  Acta Orthop Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  666-9     Citation Subset:  IM    
Department of Orthopaedic Surgery, Policlinico Umberto I, University La Sapienza, Rome, Italy.
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