Document Detail

Intralesional corticosteroid injection for central giant cell granuloma: a case report and review of the literature.
MedLine Citation:
PMID:  15884635     Owner:  NLM     Status:  MEDLINE    
Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws that is found predominantly in children and young adults. Although benign, it may be locally aggressive, causing extensive bone destruction, tooth displacement and root resorption. The common therapy is aggressive curettage, peripheral ostectomy or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. A number of alternative nonsurgical approaches have been advocated in recent years for the management of CGCGs. These include intralesional corticosteroid injections, calcitonin injections and subcutaneous alpha-interferon injections. In this article, an 1-year-old boy with a CGCG is successfully treated with corticosteroid injections and this treatment is discussed within a review of the literature.
Bahar Sezer; Banu Koyuncu; Murat Gomel; Tayfun Günbay
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  47     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2005 Jan-Mar
Date Detail:
Created Date:  2005-05-11     Completed Date:  2005-06-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  75-81     Citation Subset:  IM    
Department of Oral and Maxillofacial Surgery, Ege University Faculty of Dentistry, Izmir, Turkey.
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MeSH Terms
Adrenal Cortex Hormones / administration & dosage,  therapeutic use*
Granuloma, Giant Cell / drug therapy*
Injections, Intralesional
Mandibular Diseases / drug therapy*,  radiography
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Adrenal Cortex Hormones

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