Document Detail

Intralenticular Candida species abscess in a premature infant.
MedLine Citation:
PMID:  10704563     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To report the clinical and histopathologic findings of a premature infant with severe retinopathy of prematurity complicated by the development of an intralenticular fungal abscess. METHODS: Case report and literature review. RESULTS: A markedly premature infant developed Candida septicemia at 29 weeks postconception. Over the ensuing 10 weeks, cataract and intraocular inflammation developed sequentially in each eye, as did progressive retinopathy of prematurity with tractional retinal detachment. Pars plana vitrectomy and lensectomy revealed intralenticular Candida species abscess. CONCLUSION: Progressive cataract and intraocular inflammation in a low birth weight infant may be caused by endogenous intraocular infection secondary to systemic candidiasis. Cataract secondary to retinopathy of prematurity is rare.
G K Shah; J Vander; R C Eagle
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  129     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-04-04     Completed Date:  2000-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  390-1     Citation Subset:  AIM; IM    
Barnes Retina Consultants, Washington University, St Louis, MO, USA.
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MeSH Terms
Abscess / complications*,  pathology,  surgery
Candida albicans / isolation & purification
Candidiasis / complications*,  pathology,  surgery
Cataract / etiology
Fatal Outcome
Gestational Age
Infant, Newborn
Infant, Very Low Birth Weight
Lens Diseases / complications*,  pathology,  surgery
Multiple Organ Failure
Retinal Detachment / etiology,  ultrasonography
Retinopathy of Prematurity / complications*,  pathology,  surgery

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