Document Detail

Intralabyrinthine schwannomas: diagnosis, management, and a new classification system.
MedLine Citation:
PMID:  15021777     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To outline the diagnosis and management of intralabyrinthine schwannomas and to propose a new classification system to further define them. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center at a university hospital. PATIENTS: Twenty-eight patients seen at the institution with intralabyrinthine schwannomas between 1996 and 2002 were included in the study. INTERVENTIONS: Diagnosis was made with magnetic resonance imaging in all but one case. Our ability to detect these tumors has been greatly enhanced by the introduction of high-resolution T2-weighted magnetic resonance imaging. Treatment options were observation with serial magnetic resonance imaging versus complete surgical removal via a translabyrinthine or transotic approach. Surgery was indicated for dizziness caused by the tumor or extralabyrinthine growth. MAIN OUTCOME MEASURES: Clinical features, audiology, radiology, and management outcomes were evaluated. RESULTS: Eight patients have undergone successful surgery with removal of their tumors and resolution of symptoms. One patient chose to have stereotactic radiotherapy. Of the 20 patients who were managed with observation and serial magnetic resonance imaging, only 1 has shown significant growth requiring surgical removal. CONCLUSION: Intralabyrinthine schwannomas are uncommon tumors that mimic the clinical features of many other neurotologic conditions. A high index of suspicion and precise imaging are often required to detect these tumors. Surgical treatment is indicated for specific indications and will be needed in the minority of patients with this disorder. The classification system that we propose is helpful in both the diagnosis and the management of these tumors.
Richard J Kennedy; Clough Shelton; Karen L Salzman; H Christian Davidson; H Ric Harnsberger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology     Volume:  25     ISSN:  1531-7129     ISO Abbreviation:  Otol. Neurotol.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-15     Completed Date:  2004-07-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100961504     Medline TA:  Otol Neurotol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  160-7     Citation Subset:  IM    
Department of Otolaryngology, University of Utah, Salt Lake City, Utah 84132, USA.
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MeSH Terms
Audiometry, Pure-Tone
Auditory Threshold*
Ear Neoplasms / classification*,  diagnosis,  surgery
Labyrinth Diseases / classification*,  diagnosis,  surgery
Magnetic Resonance Imaging
Middle Aged
Neurilemmoma / classification*,  diagnosis,  surgery
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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